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1

Enzymatic incorporation of a new base pair into DNA and RNA extends the genetic alphabet

Piccirilli, Joseph A., Benner, Steven A., Krauch, Tilman, Moroney, Simon E., Benner, Steven A.

Journal:

Year:

1990

File:

PDF, 531 KB

1990

2

Chemical origins of life: Prebiotic RNA unstuck

Hernández, Armando R., Piccirilli, Joseph A.

Journal:

Nature Chemistry

Year:

2013

Language:

english

File:

PDF, 967 KB

english, 2013

3

Metal ion catalysis in the Tetrahymena ribozyme reaction

Piccirilli, Joseph A., Vyle, Joseph S., Caruthers, Marvin H., Cech, Thomas R.

Journal:

Year:

1993

File:

PDF, 488 KB

1993

4

The Mechanism of Peptidyl Transfer Catalysis by the Ribosome

Leung, Edward Ki Yun, Suslov, Nikolai, Tuttle, Nicole, Sengupta, Raghuvir, Piccirilli, Joseph Anthony

Journal:

Annual Review of Biochemistry

Year:

2011

Language:

english

File:

PDF, 840 KB

english, 2011

5

Linkage between Substrate Recognition and Catalysis during Cleavage of Sarcin/Ricin Loop RNA by Restrictocin †

Korennykh, Alexei V., Plantinga, Matthew J., Correll, Carl C., Piccirilli, Joseph A.

Journal:

Year:

2007

Language:

english

File:

PDF, 599 KB

english, 2007

6

Crystal structure of the Varkud satellite ribozyme

Suslov, Nikolai B, DasGupta, Saurja, Huang, Hao, Fuller, James R, Lilley, David M J, Rice, Phoebe A, Piccirilli, Joseph A

Journal:

Nature Chemical Biology

Year:

2015

Language:

english

File:

PDF, 2.38 MB

english, 2015

7

Efficient Synthetic Approach to Linear Dasatinib-DNA Conjugates by Click Chemistry

Li, Nan-Sheng, Gossai, Nathan, Naumann, Jordan A., Gordon, Peter M, Piccirilli, Joseph A.

Journal:

Bioconjugate Chemistry

Year:

2016

Language:

english

File:

PDF, 656 KB

english, 2016

8

Structural basis for substrate helix remodeling and cleavage loop activation in the Varkud satellite ribozyme

DasGupta, Saurja, Suslov, Nikolai B., Piccirilli, Joseph A.

Journal:

Journal of the American Chemical Society

Year:

2017

Language:

english

File:

PDF, 1.31 MB

english, 2017

9

Branched kissing loops for the construction of diverse RNA homooligomeric nanostructures

Liu, Di, Geary, Cody W., Chen, Gang, Shao, Yaming, Li, Mo, Mao, Chengde, Andersen, Ebbe S., Piccirilli, Joseph A., Rothemund, Paul W. K., Weizmann, Yossi

Journal:

Nature Chemistry

Year:

2020

Language:

english

File:

PDF, 3.29 MB

english, 2020

10

A Packing-Density Metric for Exploring the Interior of Folded RNA Molecules

Jason P. Schwans, Nan-Sheng Li, Joseph A. Piccirilli

Journal:

Angewandte Chemie

Year:

2004

Language:

english

File:

PDF, 206 KB

english, 2004

11

The Mechanism of RNA Strand Scission: An Experimental Measure of the Brønsted Coefficient, βnuc

Jing-Dong Ye, Nan-Sheng Li, Qing Dai, Joseph A. Piccirilli

Journal:

Angewandte Chemie

Year:

2007

Language:

english

File:

PDF, 168 KB

english, 2007

12

Structure and Function Converge To Identify a Hydrogen Bond in a Group I Ribozyme Active Site

Marcello Forconi, Raghuvir N. Sengupta, Mao-Chin Liu, Alan C. Sartorelli, Joseph A. Piccirilli, Daniel Herschlag

Journal:

Angewandte Chemie

Year:

2009

Language:

english

File:

PDF, 671 KB

english, 2009

13

A Packing-Density Metric for Exploring the Interior of Folded RNA Molecules

Jason P. Schwans, Nan-Sheng Li, Joseph A. Piccirilli

Journal:

Angewandte Chemie International Edition

Year:

2004

Language:

english

File:

PDF, 207 KB

english, 2004

14

The Mechanism of RNA Strand Scission: An Experimental Measure of the Brønsted Coefficient, βnuc

Jing-Dong Ye, Nan-Sheng Li, Qing Dai, Joseph A. Piccirilli

Journal:

Angewandte Chemie International Edition

Year:

2007

Language:

english

File:

PDF, 168 KB

english, 2007

15

Structure and Function Converge To Identify a Hydrogen Bond in a Group I Ribozyme Active Site

Marcello Forconi, Raghuvir N. Sengupta, Mao-Chin Liu, Alan C. Sartorelli, Joseph A. Piccirilli, Daniel Herschlag

Journal:

Angewandte Chemie International Edition

Year:

2009

Language:

english

File:

PDF, 671 KB

english, 2009

16

Characterization of the Reaction Path and Transition States for RNA Transphosphorylation Models from Theory and Experiment

Dr. Kin-Yiu Wong, Dr. Hong Gu, Dr. Shuming Zhang, Prof. Joseph A. Piccirilli, Prof. Michael E. Harris, Prof. Darrin M. York

Journal:

Angewandte Chemie International Edition

Year:

2012

Language:

english

File:

PDF, 585 KB

english, 2012

17

Inside Back Cover: Characterization of the Reaction Path and Transition States for RNA Transphosphorylation Models from Theory and Experiment (Angew. Chem. Int. Ed. 3/2012)

Dr. Kin-Yiu Wong, Dr. Hong Gu, Dr. Shuming Zhang, Prof. Joseph A. Piccirilli, Prof. Michael E. Harris, Prof. Darrin M. York

Journal:

Angewandte Chemie International Edition

Year:

2012

File:

PDF, 882 KB

2012

18

2′-C-Branched Ribonucleosides. Part 2. Synthesis of 2′-C-β-Trifluoromethyl Pyrimidine Ribonucleosides.

Nan-Sheng Li, Xiao-Qing Tang, Joseph A. Piccirilli

Journal:

Year:

2001

File:

PDF, 34 KB

2001

19

Synthesis of 2′-C-Difluoromethylribonucleosides and Their Enzymatic Incorporation into Oligonucleotides.

Jing-Dong Ye, Xiangmin Liao, Joseph A. Piccirilli

Journal:

Year:

2005

File:

PDF, 8 KB

2005

20

ChemInform Abstract: Synthesis of 2′-C-Branched Nucleosides

Nan-Sheng Li, Jun Lu, Joseph A. Piccirilli

Journal:

Year:

2010

File:

PDF, 15 KB

2010

21

A Direct Route to 3-(D-Ribofuranosyl)pyridine Nucleosides

Joseph A. Piccirilli, Tilman Krauch, Lawrence J. MacPherson, Steven A. Benner

Journal:

Helvetica Chimica Acta

Year:

1991

Language:

english

File:

PDF, 696 KB

english, 1991

22

Improved synthesis of 2′-amino-2′-deoxyguanosine and its phosphoramidite

Qing Dai, Shirshendu K. Deb, James L. Hougland, Joseph A. Piccirilli

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 219 KB

english, 2006

23

New Strategies for Exploring RNA's 2′-OH Expose the Importance of Solvent during Group II Intron Catalysis

Peter M. Gordon, Robert Fong, Shirshendu K. Deb, Nan-Sheng Li, Jason P. Schwans, Jing-Dong Ye, Joseph A. Piccirilli

Journal:

Chemistry & Biology

Year:

2004

Language:

english

File:

PDF, 293 KB

english, 2004

24

Synthesis and biochemical application of 2′-O-methyl-3′-thioguanosine as a probe to explore group I intron catalysis

Jun Lu, Nan-Sheng Li, Raghuvir N. Sengupta, Joseph A. Piccirilli

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 324 KB

english, 2008

25

Nucleotide analogues to investigate RNA structure and function

Subha R Das, Robert Fong, Joseph A Piccirilli

Journal:

Current Opinion in Chemical Biology

Year:

2005

Language:

english

File:

PDF, 344 KB

english, 2005

26

A Second Divalent Metal Ion in the Group II Intron Reaction Center

Peter M. Gordon, Robert Fong, Joseph A. Piccirilli

Journal:

Chemistry & Biology

Year:

2007

Language:

english

File:

PDF, 340 KB

english, 2007

27

The role of the cleavage site 2′-hydroxyl in the Tetrahymena group I ribozyme reaction

Aiichiro Yoshida, Shu-ou Shan, Daniel Herschlag, Joseph A Piccirilli

Journal:

Chemistry & Biology

Year:

2000

Language:

english

File:

PDF, 288 KB

english, 2000

28

Do enzymes obey the Baldwin rules? A mechanistic imperative in enzymatic cyclization reactions

Joseph A Piccirilli

Journal:

Chemistry & Biology

Year:

1999

Language:

english

File:

PDF, 485 KB

english, 1999

29

RNA seeks its maker

Piccirilli, Joseph A.

Journal:

Year:

1995

File:

PDF, 621 KB

1995

30

10.1038/42068

Sontheimer, Erik J., Sun, Sengen, Piccirilli, Joseph A.

Journal:

Year:

1997

Language:

english

File:

PDF, 385 KB

english, 1997

31

10.1038/7551

Piccirilli, Joseph A., Yoshida, Aiichiro, Sun, Sengen

Journal:

Natural Structural Biology

Year:

1999

Language:

english

File:

PDF, 297 KB

english, 1999

32

'Turning on' riboswitches to their antibacterial potential

Lea, Charles R, Piccirilli, Joseph A

Journal:

Nature Chemical Biology

Year:

2007

Language:

english

File:

PDF, 216 KB

english, 2007

33

General acid catalysis by the hepatitis delta virus ribozyme

Das, Subha R, Piccirilli, Joseph A

Journal:

Nature Chemical Biology

Year:

2005

Language:

english

File:

PDF, 443 KB

english, 2005

34

10.1038/nsb1001-893

Gordon, Peter M., Piccirilli, Joseph A.

Journal:

Natural Structural Biology

Year:

2001

Language:

english

File:

PDF, 2.11 MB

english, 2001

35

A portable RNA sequence whose recognition by a synthetic antibody facilitates structural determination

Koldobskaya, Yelena, Duguid, Erica M, Shechner, David M, Suslov, Nikolai B, Ye, Jingdong, Sidhu, Sachdev S, Bartel, David P, Koide, Shohei, Kossiakoff, Anthony A, Piccirilli, Joseph A

Journal:

Nature Structural and Molecular Biology

Year:

2010

Language:

english

File:

PDF, 1.45 MB

english, 2010

36

The electrostatic character of the ribosomal surface enables extraordinarily rapid target location by ribotoxins

Korennykh, Alexei V, Piccirilli, Joseph A, Correll, Carl C

Journal:

Nature Structural and Molecular Biology

Year:

2006

Language:

english

File:

PDF, 487 KB

english, 2006

37

Synthesis of the Phosphoramidite Derivatives of 2‘-Deoxy-2‘-C-α-methylcytidine and 2‘-Deoxy-2‘-C-α-hydroxymethylcytidine: Analogues for Chemical Dissection of RNA's 2‘-Hydroxyl Group

Li, Nan-Sheng, Piccirilli, Joseph A.

Journal:

Journal of Organic Chemistry

Year:

2004

Language:

english

File:

PDF, 272 KB

english, 2004

38

Efficient synthesis of 2′-C-α-aminomethyl-2′-deoxynucleosides

Li, Nan-Sheng, Piccirilli, Joseph A.

Journal:

Chemical Communications

Year:

2012

Language:

english

File:

PDF, 697 KB

english, 2012

39

Characterization of the Reaction Path and Transition States for RNA Transphosphorylation Models from Theory and Experiment

Dr. Kin-Yiu Wong, Dr. Hong Gu, Dr. Shuming Zhang, Prof. Joseph A. Piccirilli, Prof. Michael E. Harris, Prof. Darrin M. York

Journal:

Angewandte Chemie

Year:

2012

Language:

english

File:

PDF, 574 KB

english, 2012

40

2′-Fluoro Substituents Can Mimic Native 2′-Hydroxyls within Structured RNA

Marcello Forconi, Jason P. Schwans, Rishi H. Porecha, Raghuvir N. Sengupta, Joseph A. Piccirilli, Daniel Herschlag

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 382 KB

english, 2011

41

Leaving group stabilization by metal ion coordination and hydrogen bond donation is an evolutionarily conserved feature of group I introns

Louis Y. Kuo, Joseph A. Piccirilli

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

2001

Language:

english

File:

PDF, 547 KB

english, 2001

42

Sin Resolvase Catalytic Activity and Oligomerization State are Tightly Coupled

Kent W. Mouw, Andrew M. Steiner, Rodolfo Ghirlando, Nan-Sheng Li, Sally-J. Rowland, Martin R. Boocock, W. Marshall Stark, Joseph A. Piccirilli, Phoebe A. Rice

Journal:

Journal of Molecular Biology

Year:

2010

Language:

english

File:

PDF, 1.42 MB

english, 2010

43

The DEAH Box ATPases Prp16 and Prp43 Cooperate to Proofread 5′ Splice Site Cleavage during Pre-mRNA Splicing

Prakash Koodathingal, Thaddeus Novak, Joseph A. Piccirilli, Jonathan P. Staley

Journal:

Year:

2010

Language:

english

File:

PDF, 820 KB

english, 2010

44

Nascent Peptide in the Ribosome Exit Tunnel Affects Functional Properties of the A-Site of the Peptidyl Transferase Center

Haripriya Ramu, Nora Vázquez-Laslop, Dorota Klepacki, Qing Dai, Joseph Piccirilli, Ronald Micura, Alexander S. Mankin

Journal:

Year:

2011

Language:

english

File:

PDF, 868 KB

english, 2011

45

Identification of catalytic metal ion ligands in ribozymes

John K. Frederiksen, Joseph A. Piccirilli

Journal:

Year:

2009

Language:

english

File:

PDF, 1.80 MB

english, 2009

46

Synthesis of 2‘- C -Difluoromethylribonucleosides and Their Enzymatic Incorporation into Oligonucleotides

Ye, Jing-Dong, Liao, Xiangmin, Piccirilli, Joseph A.

Journal:

Journal of Organic Chemistry

Year:

2005

Language:

english

File:

PDF, 212 KB

english, 2005

47

Automated Solid-Phase Synthesis of RNA Oligonucleotides Containing a Nonbridging Phosphorodithioate Linkage via Phosphorothioamidites

Li, Nan-Sheng, Frederiksen, John K., Piccirilli, Joseph A.

Journal:

Journal of Organic Chemistry

Year:

2012

Language:

english

File:

PDF, 314 KB

english, 2012

48

Synthesis of 2′- C -Branched Nucleosides

Li, Nan-Sheng, Lu, Jun, Piccirilli, Joseph A.

Journal:

Organic Preparations and Procedures International

Year:

2010

Language:

english

File:

PDF, 8.52 MB

english, 2010

49

An Atomic Mutation Cycle for Exploring RNA's 2‘-Hydroxyl Group

Hougland, James L., Deb, Shirshendu K., Maric, Danijela, Piccirilli, Joseph A.

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 46 KB

english, 2004

50

Innenrücktitelbild: Characterization of the Reaction Path and Transition States for RNA Transphosphorylation Models from Theory and Experiment (Angew. Chem. 3/2012)

Dr. Kin-Yiu Wong, Dr. Hong Gu, Dr. Shuming Zhang, Prof. Joseph A. Piccirilli, Prof. Michael E. Harris, Prof. Darrin M. York

Journal:

Angewandte Chemie

Year:

2012

File:

PDF, 867 KB

2012